8k system Search Results


valproic acid  (ZeptoMetrix corporation)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
Valproic Acid, supplied by ZeptoMetrix corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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8k system  (GE Healthcare)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
8k System, supplied by GE Healthcare, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mouse anti k8α monoclonal antibody  (Santa Cruz Biotechnology)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
Mouse Anti K8α Monoclonal Antibody, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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acetaminophen  (ZeptoMetrix corporation)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
Acetaminophen, supplied by ZeptoMetrix corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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tri isobutyl phosphate tibp  (ZeptoMetrix corporation)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
Tri Isobutyl Phosphate Tibp, supplied by ZeptoMetrix corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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qiacuity 8k 96-well nanoplates  (Qiagen)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
Qiacuity 8k 96 Well Nanoplates, supplied by Qiagen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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8k system  (Biacore)
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Biacore 8k system
Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
8k System, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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8k evaluation software  (Biacore)
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Biacore 8k evaluation software
Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
8k Evaluation Software, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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8k biosensor  (Biacore)
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Biacore 8k biosensor
Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
8k Biosensor, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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8 k system  (Biacore)
90
Biacore 8 k system
Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
8 K System, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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traditional resin elegoo standard  (Elegoo Inc)
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Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
Traditional Resin Elegoo Standard, supplied by Elegoo Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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8 k instrument  (Biacore)
90
Biacore 8 k instrument
Figure 4. Treatment <t>with</t> <t>antiepileptic</t> drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with <t>valproic</t> acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.
8 K Instrument, supplied by Biacore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 4. Treatment with antiepileptic drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with valproic acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.

Journal: eneuro

Article Title: Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome

doi: 10.1523/eneuro.0066-17.2017

Figure Lengend Snippet: Figure 4. Treatment with antiepileptic drugs at 250 M. Statistically significant decreases in locomotion (distance traveled) and duration in the center of the open field were observed after treatment of zebrafish larvae with 250 M diazepam (C, D) or clemizole (G, H), but not after treatment with valproic acid (A, B) or trazodone (E, F; N 18 per group). Data are plotted in 30-s time bins showing mean SEM (left), and the 5-min total for each all individuals, are plotted on the right. p 0.001.

Article Snippet: Valproic acid, a broad spectrum antiepileptic drug (Tomson et al., 2016) commonly used in DS (Chiron and Dulac, 2011), exerts protective effects in larval or adult zebrafish exposed to the chemoconvulsant pentylenetetrazole: (1) decreasing behavioral or electrographic seizure activity and (2) improv- ing deficits in learning of a passive avoidance response (Lee et al., 2010).

Techniques: